I ngā tau tata nei, kua tino kino haere te raruraru momona o te ao. E ai ki te "Global Obesity Atlas 2025" i tukuna e te World Obesity Federation, e matapaetia ana ka piki ake te tapeke o ngā pakeke momona o te ao mai i te 524 miriona i te tau 2010 ki te 1.13 piriona i te tau 2030, he pikinga neke atu i te 115%. I runga i tēnei horopaki, kei te piki haere te maha o ngā kaihoko e rapu ana i ngā kai taiao hei āwhina i te aukati i te momona. I te marama o Hune o tēnei tau, i whakaatuhia e tētahi rangahau i whakaputaina i roto i te hautaka "npj science of food" i whakaitihia e te curcumin te kohikohinga ngako visceral i roto i ngā kiore MASH mā te aukati i te tukunga o ngā polypeptides aukati puku (GIP) i puta mai i te whara o te puku hypoxic. Ehara i te mea ka whakaratohia e tēnei kitenga he whakaaro hou mō te ārai i te momona engari ka whānui ake hoki te mākete tono o te curcumin.
Me pēhea te aukati a te curcumin i te kohikohinga o te ngako visceral? Ko te kohikohinga ngako visceral e pā ana ki te kohikohinga ngako rerekē, nui rawa rānei. Ko ngā kai warowaihā nui, ngako nui me te kore whakakori tinana ka arahi katoa ki te kore taurite o te pūngao, ka puta ai te ngako visceral nui rawa. Ko te ara kai he wāhi matua mō te mimiti ngako. Ko te kohikohinga ngako visceral he āhuatanga nui o te steatohepatitis e pā ana ki te ngoikore o te pūnaha io (MASH). E ai ki ngā rangahau, ka taea e te curcumin me ngā paturopi te whakaiti i te taumaha tinana o ngā kiore MASH, ā, he pānga tahi te curcumin me ngā paturopi.
Kua kitea e ngā rangahau tikanga ko te curcumin te nuinga o te wā ka whakaiti i te taumaha o te ngako visceral, inā koa i roto i ngā kiko perirenal. Ka ārai te curcumin i te pikinga taumaha mā te pehi i te tukunga o te GIP me te whakaiti i te taupū kiko ngako huri noa i ngā whatukuhu. Ko te whakaiti i te tukunga GIP whekau i puta mai i te curcumin ka aukati i te whakahohenga o ngā kaiwhakawhiwhi GIP, ā, ka whakaiti i te adipogenesis me te mumura i roto i te kiko ngako perirenal. Hei tāpiri, ka taea e te curcumin te whakaiti i te hypoxia whekau iti mā te tiaki i te epithelium whekau me te ārai toto, ā, ka whakaiti i te tukunga o te GIP. Hei whakamutunga, ko te pānga rongoā o te curcumin ki te ngako visceral ka whakaiti i te tukunga o te GIP mā te aukati i te hypoxia e puta mai ana i te pakaru o te ārai whekau.
Ko te curcumin, te "tohunga ārai-mumura", i ahu mai i ngā pakiaka me ngā pūtake o te Curcuma (Curcuma longa L.). He matū polyphenolic iti-taumaha-ngota, ā, e whakamahia ana hei mea kakara i roto i ngā momo kai. I te tau 1815, i tuatahi te pūrongo a Vegel me ētahi atu mō te wehenga o tētahi "matū karaka-kōwhai" mai i te pūtake o te turmeric, ā, i tapaina ko te curcumin. Nō te tau 1910 ka whakatauhia e Kazimierz me ētahi atu kaipūtaiao ko tōna hanganga matū he diferulic acylmethane. E whakaatu ana ngā taunakitanga o nāianei he pānga ārai-mumura nui tō te curcumin. Ka taea e ia te whakaatu i tōna pānga ārai-mumura mā te aukati i te ara Toll-like receptor 4 (TLR4) me tōna ara tohu nuclear factor kB (NF-kB) i raro iho, me te whakaiti i te whakaputanga o ngā āhuatanga ārai-mumura pērā i te interleukin-1 β(IL-1β) me te tumor necrosis factor -α(TNF-α). I taua wā tonu, ko ōna āhuatanga ārai-mumura e kiia ana ko te pūtake o ngā mahi koiora maha, ā, he maha ngā rangahau haumanu-mua kua tūhuratia tōna whai huatanga i roto i ngā mate mumura. I roto i ēnei, ko te mate puku mumura, te mate rumatiki, te psoriasis, te pouri, te atherosclerosis me te COVID-19 ngā kaupapa rangahau wera o nāianei.
I te whanaketanga o te mākete hou, he uaua ki te whakatutuki i te horopeta whai hua o te curcumin mā te kai anake, ā, me tango i roto i te ahua o ngā tāpiringa. Nō reira, kua tino tipu haere i roto i ngā mara o te kai hauora me ngā tāpiringa kai.
Kua whakawhanakehia hoki e Justgood Health he maha ngā tāpiringa kapia curcumin me ngā kāpū curcumin. He maha ngā kaituku kua tae mai ki te whakarite i te horopeta ahurei, i te āhua rānei o tā rātou ake waitohu.
Kua kitea e ētahi atu rangahau mō ngā painga o te curcumin, ehara i te mea ko te curcumin anake te āwhina ki te ātete i te momona engari he maha hoki ngā pānga pēnei i te ārai i te waikura, te tiaki i te roro, te whakaora i te mamae o te wheua me te tautoko i te hauora o te ngākau. Ārai i te waikura: Kua kitea e te rangahau ka taea e te curcumin te whakakore tika i ngā rauropi kore utu me te whakapai ake i te mahi mitochondrial mā te whakahohe i ngā ara pēnei i te whakangāwari i te pūmua whakahaere 3 (SIRT3), ā, ka whakaitihia te whakaputanga o te nui rawa o ngā momo hāora tauhohe (ROS) mai i te pūtake me te whakaiti pai i te kino o te waikura pūtau. Tiaki i te roro: E whakaatu ana ngā taunakitanga rangahau o nāianei he hononga tata te mumura ki te pouri. Ka taea e te curcumin te whakapai ake i ngā tohu pouri me te manukanuka o ngā tūroro e pāngia ana e te pouri. Ka taea e te curcumin te āwhina ki te ātete i te kino o ngā neuron i puta mai i te interleukin-1 β (IL-1β) me ētahi atu āhuatanga, me te whakaora i ngā whanonga rite ki te pouri i puta mai i te ahotea mau tonu. Nō reira, tera pea he mahi pai ki te tautoko i te hauora o te roro me te whakahaere i ngā kare ā-roto. Te whakaora i te mamae o te uaua me te uaua: Kua whakaatuhia e ngā rangahau ka taea e te curcumin te whakapai ake i ngā tohu haumanu o ngā kararehe tauira rumatiki me te tiaki i ngā hononga me ngā kiko uaua mā te whakaiti i te mumura. Ka taea e te curcumin te whakamamae i te mamae o ngā uaua me ngā hononga, nā te mea ka taea e ia te aukati i te tukunga o ngā mea mumura pēnei i te tumor necrosis factor -α(TNF-α) me te interleukin-1 β(IL-1β), te whakaiti i ngā urupare mumura ā-rohe, ā, mā reira ka whakamamae i ngā tohu o te pupuhi me te mamae o ngā hononga. Te tautoko i te hauora o te ngākau me te ngākau: Mō te pūnaha ngākau me te ngākau, ka taea e te curcumin te mahi mā te whakahaere i ngā ngako toto, te whakaiti i te cholesterol katoa o te toto, ngā triglycerides me ngā taumata cholesterol lipoprotein iti-kiato, me te whakanui ake i ngā taumata cholesterol lipoprotein teitei-kiato. Hei tāpiri, ka taea hoki e te curcumin te aukati i te tipu o ngā pūtau uaua maeneene me ngā urupare mumura, he mea āwhina ki te aukati i te putanga mai me te whanaketanga o ngā mate ngākau me te ngākau pēnei i te atherosclerosis.
Wā tuku: Hanuere-08-2026