Ko te Astaxanthin (3,3'-dihydroxy-beta,beta-carotene-4,4'-dione) he carotenoid, he lutein te ingoa, e kitea ana i roto i te tini o ngā moroiti me ngā kararehe moana, ā, i wehea tuatahitia mai i ngā kōura e Kuhn rāua ko Sorensen. He tae wairewa-ngako e āhua ana mai i te karaka ki te whero pouri, ā, kāore he huaora A i roto i te tinana tangata.
Ko ngā puna tūturu o te astaxanthin ko te rimurimu, te rewena, te hāmana, te taraute, te krill me te kōura. Ko te nuinga o te astaxanthin hokohoko ka ahu mai i te rewena Fife, te rimurimu whero me te hanganga matū. Ko tētahi o ngā puna pai rawa atu o te astaxanthin tūturu ko te chlorella whero whāngai ua, me te ihirangi astaxanthin tata ki te 3.8% (mā te taumaha maroke), ā, he puna pai hoki ngā hāmana mohoao mō te astaxanthin. Ko te hanga hangai tonu te puna matua o te astaxanthin nā te utu nui o te whakatipu nui o Rhodococcus rainieri. Ko te ngohe koiora o te astaxanthin i hangaia i te hangai he 50% noa iho i tērā o te astaxanthin tūturu.
Kei te noho te Astaxanthin hei stereoisomers, hei isomers āhuahanga, hei āhua kore utu, hei āhua esterified hoki, ko ngā stereoisomers (3S,3'S) me te (3R,3'R) ngā mea tino nui i te taiao. Ka puta te (3S,3'S)-isomer i te Rhodococcus rainieri, ā, ka puta te (3R,3'R)-isomer i te rewena Fife.
Astaxanthin, te wera o te wā
Ko te Astaxanthin te matū matua i roto i ngā kai mahi i Hapani. I kitea i roto i ngā tatauranga a te FTA mō ngā whakapuakitanga kai mahi i Hapani i te tau 2022, ko te astaxanthin te nama 7 i roto i ngā matū 10 matua e pā ana ki te auau o te whakamahinga, ā, i whakamahia nuitia i roto i ngā mara hauora o te tiaki kiri, te tiaki kanohi, te whakamamae i te ngenge, me te whakapai ake i te mahi hinengaro.
I ngā Tohu Kai Kai Āhia o te tau 2022 me te 2023,Hauora Justgood I mōhiotia te kai o te astaxanthin tūturu hei kai pai rawa atu o te tau mō ngā tau e rua karapīpiti, ko te kai pai rawa atu i te ara mahi hinengaro i te tau 2022, me te kai pai rawa atu i te ara ataahua ā-waha i te tau 2023. Hei tāpiri, i whakarārangihia te kai i roto i te rārangi poto o ngā Tohu Kai Kai Āhia - te ara Pakeke Hauora i te tau 2024.
I ngā tau tata nei, kua tīmata hoki te werawera o ngā rangahau mātauranga mō te astaxanthin. E ai ki ngā raraunga a PubMed, i te tau 1948, i puta ngā rangahau mō te astaxanthin, engari kāore i te tino arohia, mai i te tau 2011, ka tīmata te arotahi a te ao mātauranga ki te astaxanthin, me te neke atu i te 100 ngā whakaputanga ia tau, me te neke atu i te 200 i te tau 2017, neke atu i te 300 i te tau 2020, me te neke atu i te 400 i te tau 2021.
Pūtake o te ahua: PubMed
Mō te mākete, e ai ki ngā tirohanga mākete o Future, e kiia ana ko te rahi o te mākete astaxanthin o te ao e tata ana ki te USD 273.2 miriona i te tau 2024, ā, e matapaetia ana ka eke ki te USD 665.0 miriona i te tau 2034, i te CAGR o te 9.3% i te wā matapae (2024-2034).
Te kaha ārai mate teitei
Nā te hanganga ahurei o te Astaxanthin ka tino kaha ki te ārai i te mate. Kei roto i te Astaxanthin ngā here takirua honohono, ngā rōpū hydroxyl me te ketone, ā, he lipophilic me te hydrophilic hoki. Ko te here takirua honohono kei waenganui o te pūhui ka whakarato i ngā irahiko, ā, ka tauhohe ki ngā rauropi kore utu hei huri i a rātou hei hua pumau ake, hei whakamutu hoki i ngā tauhohenga mekameka rauropi kore utu i roto i ngā momo rauropi. He pai ake tana mahi koiora i ērā atu rauropi nā tōna kaha ki te hono atu ki ngā kiriuhi pūtau mai i roto ki waho.
Te wāhi o te astaxanthin me ētahi atu antioxidants i roto i ngā kiriuhi pūtau
He nui te mahi ārai-mate a te Astaxanthin, ehara i te mea mā te tango tika i ngā rauropi kore utu anake, engari mā te whakahohenga hoki o te pūnaha ārai ārai-mate pūtau mā te whakahaere i te ara o te tauwehenga erythroid 2 (Nrf2) o te matū karihi. Ka ārai te Astaxanthin i te hanganga o te ROS, ā, ka whakahaere hoki i te whakaaturanga o ngā whākōkī e aro ana ki te ahotea waikura, pērā i te heme oxygenase-1 (HO-1), he tohu mō te ahotea waikura. Ka whakahaeretia te HO-1 e te maha o ngā tauwehenga whakawhiti e aro ana ki te ahotea, tae atu ki te Nrf2, e herea ana ki ngā huānga e aro ana ki te ārai-mate i roto i te rohe whakatairanga o ngā whākōkī pākia e whakakore ana i te paitini.
Ko te whānuitanga katoa o ngā painga me ngā whakamahinga o te astaxanthin
1) Te whakapai ake i te mahi hinengaro
He maha ngā rangahau kua whakaū i te mea ka taea e te astaxanthin te whakaroa, te whakapai ake rānei i ngā ngoikoretanga hinengaro e pā ana ki te koroheketanga noa, te whakaiti rānei i te pathophysiology o ngā mate neurodegenerative. Ka taea e te astaxanthin te whiti i te arai toto-roro, ā, kua whakaatuhia e ngā rangahau ka kohia te astaxanthin kai i roto i te hippocampus me te cortex roro o te roro kiore i muri i te kai kotahi me te kai auau, ka pā pea ki te pupuri me te whakapai ake i te mahi hinengaro. Ka whakatairanga te astaxanthin i te whakahoutanga o ngā pūtau io me te whakanui ake i te whakaaturanga ira o te glial fibrillary acidic protein (GFAP), te microtubule-associated protein 2 (MAP-2), te brain-derived neurotrophic factor (BDNF), me te growth-associated protein 43 (GAP-43), ngā pūmua e whai wāhi ana ki te whakaora i te roro.
Ka mahi tahi ngā Kāpū Astaxanthin Justgood Health me te Cytisine me te Astaxanthin mai i te Ngāherehere Rākau Whero, hei whakapai ake i te mahi hinengaro o te roro.
2) Tiaki Kanohi
He mahi ārai-mate kei roto i te Astaxanthin e whakakore ana i ngā ngota rauropi kore-hāora, ā, e tiaki ana hoki i ngā kanohi. Ka mahi tahi te Astaxanthin me ētahi atu carotenoid e tautoko ana i te hauora o ngā kanohi, inā koa ko te lutein me te zeaxanthin. Hei tāpiri, ka whakanui ake te astaxanthin i te tere o te rere o te toto ki te kanohi, ka taea ai e te toto te whakahoki anō i te hāora ki te retina me te kiko o te kanohi. Kua whakaatuhia e ngā rangahau ko te astaxanthin, me te hono atu ki ētahi atu carotenoid, ka tiaki i ngā kanohi mai i ngā kino puta noa i te whānuitanga o te rā. Hei tāpiri, ka āwhina te astaxanthin ki te whakamamae i te mamae o ngā kanohi me te ngenge o te tirohanga.
Ngā Kapene Ngāwari Tiaki Mārama Kikorangi Justgood Health, Ngā kai matua: lutein, zeaxanthin, astaxanthin.
3) Te Tiaki Kiri
He mea nui te ahotea waikura hei whakaoho i te koroheketanga o te kiri tangata me te kino o te kiri. Ko te tikanga o te koroheketanga ā-roto (wā) me te koroheketanga ā-waho (mārama) ko te whakaputanga o te ROS, mā roto i te pākia o te waikura, me te ā-waho mā roto i te pānga ki ngā hihi ultraviolet (UV) o te rā. Ko ngā mahi waikura i roto i te koroheketanga o te kiri ko te kino o te DNA, ngā urupare mumura, te whakaiti i ngā antioxidants, me te whakaputanga o ngā matrix metalloproteinases (MMP) e whakangaro ana i te collagen me te elastin i roto i te dermis.
Ka taea e te astaxanthin te aukati i te kino o te waikura i puta mai i ngā rauropi kore utu me te whakaoho o te MMP-1 i roto i te kiri i muri i te pānga o te hihi UV. Kua whakaatuhia e ngā rangahau ka taea e te astaxanthin mai i te Erythrocystis rainbowensis te whakanui ake i te ihirangi collagen mā te aukati i te whakaaturanga o te MMP-1 me te MMP-3 i roto i ngā pūtau kiri tangata. Hei tāpiri, i whakaitihia e te astaxanthin te kino o te DNA i puta mai i te hihi UV, ā, i whakanui ake i te whakatikatika DNA i roto i ngā pūtau e pāngia ana e te hihi UV.
Kei te whakahaerehia e Justgood Health ētahi rangahau i tēnei wā, tae atu ki ngā kiore kore huruhuru me ngā whakamātautau tangata, ā, kua whakaatuhia katoatia e ēnei rangahau ka whakaitihia e te astaxanthin te kino o te UV ki ngā paparanga hohonu o te kiri, e puta ai ngā tohu o te koroheketanga o te kiri, pērā i te maroke, te kiri e totoro ana me ngā kita.
4) Kai hākinakina
Ka taea e te Astaxanthin te whakateretere i te whakatikatika i muri i te whakakori tinana. Ina whakakori tinana te tangata, ka puta he nui o te ROS i roto i te tinana, ā, ki te kore e tangohia i te wā tika, ka kino pea ngā uaua me te whakaora tinana, engari ka taea e te mahi antioxidant kaha a te astaxanthin te tango i te ROS i te wā tika me te whakatika tere ake i ngā uaua kua pakaru.
Kei te whakauru mai a Justgood Health i tana Astaxanthin Complex hou, he ranunga maha o te konupūmā glycerophosphate, te huaora B6 (pyridoxine), me te astaxanthin e whakaiti ana i te mamae o te uaua me te ngenge i muri i te whakakori tinana. Ko te hanganga e aro ana ki te Whole Algae Complex a Justgood Health, e tuku ana i te astaxanthin tūturu e kore e tiaki noa i ngā uaua mai i te kino waikura, engari e whakarei ake ana hoki i te mahi uaua me te whakapai ake i te mahi hākinakina.
5) Hauora o te Ngākau
Ko te ahotea waikura me te mumura te tohu o te pathophysiology o te mate ngakau atherosclerotic. Ko te kaha antioxidant tino pai o te astaxanthin ka taea te aukati me te whakapai ake i te atherosclerosis.
Ka āwhina ngā Kapene Ngāwari Astaxanthin Taiao Kaha Toru a Justgood Health ki te pupuri i te hauora o te ngākau mā te whakamahi i te astaxanthin taiao i ahu mai i te rimurimu whero āniwaniwa, ko ngā kai matua ko te astaxanthin, te hinu kokonati wahine parakore me ngā tocopherol taiao.
6) Te Whakahaere i te Ārai Mate
He tino tairongo ngā pūtau pūnaha ārai mate ki te kino o ngā rauropi kore utu. Ka tiakina e te astaxanthin ngā parepare o te pūnaha ārai mate mā te aukati i te kino o ngā rauropi kore utu. I kitea i roto i tētahi rangahau ka puta he immunoglobulin i roto i ngā pūtau tangata, ā, ki te tāpirihia te astaxanthin mō ngā wiki e 8 i roto i te tinana tangata, ka piki ake ngā taumata astaxanthin i roto i te toto, ka piki ake ngā pūtau T me ngā pūtau B, ka heke te kino o te DNA, ā, ka tino heke te pūmua C-reactive.
Ko ngā karāhe ngohengohe astaxanthin, he astaxanthin mata, e whakamahi ana i te hihi o te rā māori, te wai kua tātarihia e te rangitoto me te pūngao o te rā hei whakaputa i te astaxanthin parakore, hauora hoki, hei āwhina i te whakapakari i te ārai mate, te tiaki i te tirohanga me te hauora o ngā hononga.
7) Whakamamae i te ngenge
I kitea i roto i tētahi rangahau matapōkere, matapo-rua, whakahaere-placebo, whakawhiti-rua, e whā wiki te roa, i whakatairanga te astaxanthin i te whakaoranga mai i te ngenge hinengaro i puta mai i te tirohanga matapōkere (VDT), me te whakaiti i ngā taumata phosphatidylcholine hydroperoxide (PCOOH) plasma teitei i te wā o te mahi hinengaro me te mahi tinana. Ko te take pea ko te mahi antioxidant me te tikanga anti-inflammatory o te astaxanthin.
8) Te tiaki i te ate
He pānga ārai me te whakapai ake a te Astaxanthin ki ngā raruraru hauora pēnei i te fibrosis ate, te whara o te ate ischemia-reperfusion, me te NAFLD. Ka taea e te Astaxanthin te whakahaere i ngā momo ara tohu, pēnei i te whakaiti i te mahi JNK me te ERK-1 hei whakapai ake i te ātete ki te insulin ate, te aukati i te whakaaturanga PPAR-γ hei whakaiti i te hanganga ngako ate, me te whakaheke i te whakaaturanga TGF-β1/Smad3 hei aukati i te whakahohenga HSC me te fibrosis ate.
Te tūnga o ngā ture i ia whenua
I Haina,astaxanthin Mai i te pūtake o te pūngāwerewere whero āniwaniwa ka taea te whakamahi hei wāhanga kai hou i roto i ngā kai whānui (haunga ngā kai pēpi), hei tāpiritanga, ka whakaaetia hoki e te Hononga o Amerika, Kānata me Hapani te whakamahi i te astaxanthin i roto i ngā kai.
Wā tuku: Hakihea-05-2024